Antigen is a biotech pharmaceutical company employed by world governments to contain and experiment on Vampires and Lycans after they are captured, seen in Underworld: Awakening. In reality, Antigen is a front operated by the Lycans to fool governments into believing they are extinct, as to turn the humans' attention to killing the old adversary of the Lycans, the Vampires. The head of Antigen is Dr. Jacob Lane. Their headquarters are likely located in Hungary.
12 years after the capture of Selene and Michael Corvin, Antigen has discovered that Hybrids that carry the Corvinus Strain have immunity to silver, a substance which Lycans are allergic to. With this information, Jacob Lane and his son, Quint, have made themselves into Lycan-Corvinus Strain Hybrids. However, to finish the immunity, Antigen must harvest the organs of a young Hybrid named Eve.
On the eve of the planned surgery date for harvesting Eve's organs, the girl breaks free of Antigen's headquarters and frees her mother, Selene. Selene crashes through the facility, killing several guards, before finally fleeing through a window. Antigen tracks Selene, hoping she will lead them to Eve. They eventually follow her to a hidden Vampire Coven, where they are able to successfully kidnap Eve.
However, before they can harvest the antidote, Selene attacks Antigen's headquarters, forcing the doctors to move Eve to a new location. Before they can escape the company's parking lot, Selene attacks the van carrying her daughter, and she and Eve kill everyone in the van, including Jacob and Quint Lane.
The fate of Antigen after the death of its head doctor is unknown.
Antigen workers, both Lycans and human personnel, are trained to fight and secure test subjects. One of Antigen's soldiers is seen to be able to work a flame-thrower, indicating they often use fire to kill Vampires.
|Selene - Eve - David - Jacob Lane - Quint Lane|
|Thomas - Lida - Alan - Michael Corvin - Detective Sebastian - Olivia - Edward Vronski - Corvinus Clan|
|Vampire - Lycan - Hybrid - Immortal - Human|
|Swords - Sleeping Gas - Silver Nitrate Bomb - Modified Beretta 92FS - Whips - Shurikens - Silver|
|Antigen Headquarters - Thomas's Coven - Cryogenic Chamber - Army Surplus Store - Pier 9|
|Corvinus Strain - Death Dealer - Vampire Elder - Blood Memories - The Purges - Antigen|
|Music - Quotes - Images - Soundtrack - Score|