The IMI Desert Eagle Mark VII is a semi-automatic magnum pistol and variant of the Desert Eagle weapon series. This variant fires a .44 Magnum ammunition from an 8-round magazine. The type that were used in the film were all Nickel.
In the film Underworld the Desert Eagle is seen in the hands of mostly the Lycans. The first one to carry the gun was Trix and it was his gun that Selene took back to Kahn in order for him to analyze the new UV Rounds. Eventually Lucian is seen taking up the Desert Eagle and loading up on UV Rounds in order to combat Viktor and his Death Dealers. He's then shot by Kraven's Heckler & Koch USP MATCH loaded with Silver Nitrate Ammunition.